Particle size measurement with S-MLS in higly viscous media

Introduction Size determination of objects embedded in highly viscous media, such as gels, is very limited with Dynamic Light Scattering (DLS). This application note shows how Turbiscan® technology based on Static Multiple Light Scattering (SMLS) can easily and quickly determine the mean diameter of objects in a highly viscous medium in a range of 10nm to 1000µm. The example presented here, focuses on vesicles introduced into a biopolymer gel for pharmaceutical or cosmetic application (skin application).