EFFECT OF ELECTROLYTE INTRODUCTION ON PARENTERAL EMULSION STABILITY

INTRODUCTION Lipid injectable emulsions for therapeutic nutrition must cover all the individual needs and are an essential source of fatty acids, as well as a daily source of calories. The therapeutic nutrition can be done with successive or simultaneous administration of lipid emulsion, electrolyte and minerals. The simultaneous administration of a dispersion containing all the nutriments requires the validation of the compatibility between the nutritive elements and the stability of the lipid emulsion in the dispersion. These emulsions have been used in the clinical setting for almost 50 years, but despite this, there are no established official standards governing pharmaceutical quality. The stability of a lipid emulsion with different concentration of calcium chloride (CaCl2) was evaluated using the Turbiscan technology.