Liver fibrosis is caused by non-alcoholic fatty liver disease
(NAFLD); the usual way of assessing such damage is via a
liver biopsy, which is invasive and an uncomfortable procedure for patients. Mitochondrial dysfunction plays a role
in liver fibrosis, so an alternative approach to assessing
liver damage is the use of an isotopic breath test with a
Sercon ABCA2.The 13C-ketoisocaproate (13C-KICA) breath test evaluates
hepatic mitochondrial function. The aim of this study
was to determine associations between the 13C-KICA
breath test and measurement of liver fibrosis.
